General Information

  • ID:  hor004276
  • Uniprot ID:  A0A1S4FE51
  • Protein name:  Tachykinin-related peptide 2
  • Gene name:  5568206
  • Organism:  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
  • Family:  Tachykinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  VPSGFTGMR
  • Length:  9
  • Propeptide:  MNTIRIGTLVLLMLNIYFSYADPGVKSDVTKNIRDKRDHYYSEGVGNFYSNFNEPDNAITTVLPLLDTDGTSKVANDVPTDNDDGEDDALVSHSLDDEFHYFRPNPDSGVEGKLNYDWNNDDTNENRLDVRGKKNIPFYPLRLYPKRAPSGFLGLRGKKYYYNGAKRVPSGFTGMRGKKAFYDMNSSFDDNTNQLELTKDIHFDELLQRERAFLEELYRIHQIEQEISNNPSISTFQTSEKRAPSGFLGMRGKKATEDSSSNSETKRAPSGFLGLRGKRANIDDYIEGNKRTTFTSYFGMQGNKEPLILGSDKIYSQLNRMNWPVNDRLQMDRTPPKRVPNGFLGVRGKKWTDTIYDE
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A1S4FE51-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor004276_AF2.pdbhor004276_ESM.pdb

Physical Information

Mass: 109397 Formula: C41H66N12O12S
Absent amino acids: ACDEHIKLNQWY Common amino acids: G
pI: 10.55 Basic residues: 1
Polar residues: 4 Hydrophobic residues: 2
Hydrophobicity: 5.56 Boman Index: -964
Half-Life: 100 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 32.22
Instability Index: 3387.78 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  20163154
  • Title:  Neuropeptidomics of the Mosquito Aedes Aegypti